Effect of Silibum marianum seed and Thymus vulgaris powders and their combination on some carcass chracteristices, blood metaboiltes and immune system responses of broilers fed aflatoxin B1 contaminated diet

Document Type : Research Paper

Authors

1 MSc. Graduated student, Department of Animal Science, Faculty of Agricultural Sciences, University of Urmia, Urmia, Iran

2 Assistant Professor, Department of Animal Science, Faculty of Agricultural Sciences, University of Urmia, Urmia, Iran

3 Associate Professor, Department of Poultry Science, Faculty of Agricultural Sciences, University of Tarbiat Modares, Tehran, Iran

Abstract

In order to assess the effects of Silibum marianum seed(SMS) and Thymus vulgaris (TM)powderson carcass traits, some blood metabolites and immune system responses of chickens which fed by aflatoxin B1 (AFB1) contaminated diet (2 mg/kg) during 1 to 21 d of age, a total of 200 male broilers (Ross 308) were used in completely randomized design with five treatments and four replicates (10 birds per replicate). The experimental dietary treatments included: 1) control diet (without contamination, negative control), 2) AFB1 contaminated diet (positive control), 3) AFB1 contaminated diet + 1% SMS, 4) AFB1 contaminated diet + 1 % TM, 5) AFB1 contaminated diet + 1% SMS + 1 % TM. The results of current study indicated that feeding AFB1 containing diet increased liver weight compared with 1 and 3 groups and supplementation of AFB1 contaminated diet with SMS attenuated effects of AFB1 on liver weight (P<0.05).  The lowest glucose level was observed in positive control group birds (P<0.01). Addition of SMS, TM and their combination to AFB1 contaminated diets caused a significant decrease in plasma alanine aminotransferase concentration versus positive control group (P<0.01). The highest aspartate aminotransferase level was observed in the positive control group and supplementation of SMS caused this parameter restored to level similar to negative control group (P<0.01). Total antibody level was not significantly affected by dietary treatment (P>0.05), while supplementation of AFB1 contaminated diets with SMS and SMS and TM combination significantly increased lymphocyte proliferation test and respiratory burst in monocytes (P<0.01). In general, these results confirmed the positive impact of SMS, TM and their combination in reducing the adverse effects of AFB1 on liver weight, blood metabolites and immune system response in broilers.

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References

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Animal Production Research
Volume 7, Issue 1
June 2018
Pages 53-66

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