اثر تغذیه طولانی مدت کلرید کادمیوم بر غلظت آن در بافت‌ها، ادرار و مدفوع و غلظت عناصر آهن، روی و مس در بافت‌های گوساله‌های نر هلشتاین

نوع مقاله : مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری گروه علوم دامی، دانشکده کشاورزی، دانشگاه فردوسی مشهد

2 استاد گروه علوم دامی، دانشکده کشاورزی، دانشگاه فردوسی مشهد

چکیده

در این آزمایش تأثیر تغذیه طولانی مدت عنصر کادمیوم بر غلظت کادمیوم در بافت­های مختلف کبد، کلیه، ریه، عضلات، استخوان و خون و غلظت آن در ادرار و مدفوع و همچنین اثر آن بر غلظت عناصر آهن، روی و مس در بافت­های کبد، کلیه، استخوان و عضلات درگوساله­ های نر هلشتاین مورد بررسی قرار گرفت. تعداد 20 رأس گوساله نر هلشتاین با میانگین وزن 203 کیلو­گرم و سن 185 روزدر قالب یک طرح کاملاً تصادفی با چهار گروه و پنج تکرار مورد مطالعه قرار گرفتند. جیره غذایی هر چهار گروه یکسان بود و فقط مقدار کادمیوم اضافه شده به جیره آنها متفاوت بود (به ­ترتیب صفر، 2، 5 و 10 میلی­ گرم در کیلوگرم ماده خشک خوراک). پس از پایان آزمایش (300 روز)، گوساله­ ها ذبح شدند و نمونه­ های بافتی از کبد، کلیه، ریه، استخوان قلم پا، عضله ران، عضله قلب و طحال گرفته شد. همچنین در سه روز پایانی، نمونه­ های خون، ادرار و مدفوع گوساله‌ها جمع ­آوری گردید. نتایج نشان داد که با افزایش مقدار کادمیوم جیره، غلظت کادمیوم در بافت­ها و به ­ویژه کبد و کلیه‌ها به­ شکل معنی ­داری افزایش یافت (05/0P<). با افزایش مصرف کادمیوم، غلظت کادمیوم ادرار و مدفوع نیز افزایش یافت (05/0P<). همچنین همراه با افزایش مصرف کادمیوم، مقدار مس کبد و استخوان و مقدار آهن و روی کلیه­ ها و کبد، کاهش معنی­ داری داشت (05/0P<). به­ طور کلی می ­توان چنین نتیجه­ گیری کرد که آلودگی محیط و به­ویژه خاک و آب با کادمیوم با افزایش ورود آن به تولیدات دامی و طبیعتاً بدن انسان و بروز اثرات سمی آن همراه خواهد بود.

کلیدواژه‌ها

موضوعات


عنوان مقاله [English]

The effect of long-term dietary cadmium chloride on cadmium concentration in tissues, urine and feces and concentration of iron, zinc and copper in tissues in Holstein male calves

نویسندگان [English]

  • M. A. Khorashadi Zadeh 1
  • R. Valizadeh 2
  • A. A. Naserian 2
1 PhD Student, Department of Animal Sciences, Faculty of Agricultural Science, Ferdowsi University of Mashhad, Iran
2 Professor, Department of Animal Sciences, Faculty of Agricultural Science, Ferdowsi University of Mashhad, Iran
چکیده [English]

The effects of long-term consumption of cadmium (Cd) on its concentration in liver, kidney, lunges and muscles tissues, blood, urine and feces and also iron, zinc and copper content in liver, kidney, bones and muscles tissues in Holstein male calves were studied in this study. Twenty Holstein male calves (with average body weight of 203 kg and age of 185 days) were allocated to four groups in a completely randomized design. All of the animals were fed a similar diet but differing in concentration of Cd (0, 2, 5 and 10 mg/kg of dry matter) for a period of 300 days. The blood, urine and feces of all experimental calves were sampled at the end of last 3 days of the experimental period. The calves were slaughtered at the end of experimental period and their liver, kidney, lunges, shinbone, thigh and heart muscles and spleen were also sampled. The results revealed that, Cd concentration in liver and kidney tissues urine, and feces samples were significantly (P<0.05) higher than the control calves. With increasing Cd intake, the copper concentration in liver and bone and the zinc concentration in liver and kidney decreased significantly (P<0.05). It was concluded that soil and water pollution with Cd could increase its concentration in animal body and products which is harmful for their consumers.

کلیدواژه‌ها [English]

  • cadmium
  • Heavy metals
  • Holstein male calves
  • Liver
  • Kidney
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